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PulseCO Algorithm

The PulseCO pulse “power” derivation of cardiac output from the arterial waveform

Key Supporting Science & Studies

P1.1. Hamilton TT, Huber LM, Jessen ME. (2002) PulseCO: A Less-Invasive Method to Monitor Cardiac Output From Arterial Pressure After Cardiac Surgery. Ann Thorac Surg; 74:S1408-12

P1.2. Rhodes A, Sunderland R (2005) Arterial Pulse Pressure Analysis: The LiDCOplus System. Update in Intensive Care and Emergency Medicine 42, 183 -192.

P1.3. Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED (2005) Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial. Crit Care 9 (6) 687-693

P1.4. Pittman J, Bar Yosef S, SumPing J, Sherwood M, Mark J (2005) Continuous cardiac output monitoring with pulse contour analysis: A comparison with lithium indicator dilution cardiac output measurement. Crit Care Med. 33 (9) 2015-2021

P1.5. Belloni L, Pisano A, Natale A, Piccirillo M, Piazza L, Ismeno G, De Martino G (2007) Assessment of Fluid-Responsiveness Parameters for Off-Pump Coronary Artery Bypass Surgery: A Comparison Among LiDCO, Transesophageal Echocardiography, and Pulmonartery Catheter. J Cardiothorac Vasc Anesth. 2008 Apr;22(2):243-8.

P1.6. O’Brien T (2007) LiDCO - From the laboratory to protocolized goal directed therapy. Annual Reviews in Control 31, 303 -310

P1.7. Costa MG, Della Rocca G, Chiarandini P, Mattelig S, Pompei L, Barriga MS, Reynolds T, Cecconi M, Pietropaoli P (2007) Continuous and intermittent cardiac output measurements in hyperdynamic conditions: pulmonary artery catheter versus lithium dilution technique. Intensive Care Medicine DOI 10.1007/s00134-007-0878-6

P1.8. Missant C, Rex S, Wouters P. (2008) Accuracy of cardiac output measurements with pulse contour analysis (PulseCO) and Doppler echocardiography during off-pump coronary artery bypass grafting. European Journal of Anaesthesiology 25( 3): 243-248

P1.9. Kemps H, Thijssen E, Schep G, Sleutjes B,De Vries W, Hoogeveen A, Wijn P, Doevendans P. (2008) Evaluation of two methods for continuous cardiac output assessment during exercise in chronic heart failure patients. Journal of Applied Physiology 105: 1822-1829

P1.10. Marquez J, McCurry K, Severyn D, Pinsky M. (2008). Ability of Pulse Power, Esophageal Doppler and Arterial Pulse Pressure to Estimate Rapid Changes in Stroke Volume in Humans. Crit Care Med 36(11) 3001 – 3007

P1.11. Mills E, Jonas M, Wolff C, O’Brien T (2010) PulseCO consistency: variation in calibration factor over 24 and 48 hours. Poster presentation ISICEM, Brussels. Critical Care 14(1), p101

P1.12. Jonas M, Mills E, Wolff C, O’Brien T (2010) Effect of cardiac arrhythmias on PulseCO calibration and performance. Poster presentation ISICEM, Brussels. Critical Care 14(1), p102

P1.13. Green D, Paklet L (2010) Latest developments in peri-operative monitoring of the high-risk major surgery patient. International Journal of Surgery 8 90-99

P1.14. Abdel-Galil K, Craske D, McCaul J (2010) Optimisation of intraoperative haemodynamics: early experience of its use in major head and neck surgery. Brit Journal of Oral and Maxillofacial Surgery 48 (3) 189-191

P1.15. Wyffels P, Sergeant P, Wouters P (2010) The value of pulse pressure and stroke volume variation as predictors of fluid responsiveness during open chest surgery. Anaesthesia 65: 704:709

P1.16. Hata JS, Shelsky CS, Frazier J, Wang J, Nickel EJ (2010) Clinical Outcomes of Dynamic versus Static Monitors in Shock. Proceedings of the 2010 Annual Meeting of the ASA

P1.17. Purushothaman B, O’Brien T, Green D (2010) The Hemodynamic Effects of Anesthetic Induction and Their Correlation with Changes in Depth of Anesthesia. Proceedings of the 2010 Annual Meeting of the ASA

P1.18. Koff M, Richard K, Novak M, Canneson M, Dodds T (2010) Elevated PPV Predicts an Increased Length of Stay and Morbidity during High risk Abdominal Surgery. Proceedings of the 2010 Annual Meeting of the ASA

P1.19 Hadian M, Severyn D, Pinsky M. The effects of vasoactive drugs on pulse pressure and stroke volume variation in postoperative ventilated patients. (2011) Journal of Critical Care. Jun;26(3):328.e1-8. doi: 10.1016/j.jcrc.2010.08.018

P1.20 Dyer R, Piercy J, Reed A, Strathie G, Lombard C, Anthony J, James M (2011) Comparison between pulse waveform analysis and thermodilution cardiac output determination in patients with severe pre-eclampsia. Brit Journal of Anaesthesia 106 (1) 77 – 81

P1.21 Hata J, Stotts C, Shelsky C, Bayman E, Frazier A, Wang J, Nickel E. (2011) Reduced mortality with noninvasive hemodynamic monitoring of shock. J Crit Care vol 26(2):224. E1-8

P1.22 Lobo S et al., (2011) Restrictive strategy of intraoperative fluid maintenance during optimization of oxygen delivery decreases major complications after high risk surgery. Critical Care vol 15:R226 doi: 10.1186/cc10466

P1.23 Cecconi M, Monti G, Hamilton M, Puntis M, Dawson D, Tuccillo M, Della Rocca G, Grounds R, Rhodes A (2012) Efficacy of functional hemodynamic parameters in predicting fluid responsiveness with pulse power analysis in surgical patients. Minerva Anestesiol 78(5): 527-33

P1.24 Preston SR, Markar SR, Baker CR, Soon Y, Singh S and Low DE (2013) Impact of multidisciplinary standardized clinical pathway on perioperative outcomes in patients with oesophageal cancer. Br J Surg Jan;100(1):105-12. Doi: 10.1002/bjs.8974

P1.25 Jones C, Kelliher L, Dickinson M, Riga A, Worthington T, Scott M J, Vandrevala T, Fry C H, Karanjia N and Quiney N (2013) Randomized clinical trial on enhanced recovery versus standard care following open liver resection. Br J Surg Jul;100(8):1015-24. Doi: 10.1002/bjs.9165

P1.26 Green D, Bidd H, Rashid H (2014) Multimodal intraoperative monitoring: An observational case series in high risk patients undergoing major peripheral vascular surgery. International Journal of Surgery 12 (2014) 231 – 236

P1.27 Dunne D, Yip V, Jones R, McChesney E, Lythgoe D, Psarelli E, Jones L, Lacasia-Purroy C, Malik H, Poston G, Fenwick S (2014) Enhanced Recovery in the Resection of Colorectal Liver Metastases. Journal of Surgical Oncology DOI: 10.1002/jso.23616

P1.28 Miller T, Thacker J, White W, Mantyh C, Migaly J, Jin J, Roche A, Eisenstein E, Edwards R, Anstrom K, Moon R, Gan TJ and Enhanced Recovery Study Group (2014) Reduced Length of Hospital Stay in Colorectal Surgery after Implementation of an Enhanced Recovery Protocol. Anesthesia & Analgesia 118 (5) 1052 – 1061

P1.29 Ebm C, Cecconi M, Sutton L, Rhodes A (2014) A Cost-Effectiveness Analysis of Postoperative Goal-Directed Therapy for High-Risk Surgical Patients. Critical Care Medicine 42 (5) 1194 - 1203'

Further Presented & Published PulseCO Studies

P2.1. Grauhan O, Mappes A, Gründel M, Jurmann M, Weng Y, Kuppe H, Hetzer R. (2001) Hemodynamic Monitoring Using the PulseCO™ System During Cardiac off-pump Surgery. PulseCO™ & Robotic Surgery Leipzig Meeting 2001 Thoracic and Cardiovascular Surgeon 49(1): 56

P2.2. Jonas M, Bruce R, Knight J, Kelly F, O'Brien T, Band D. (2001) Comparison of cardiac output measurements using a continuous arterial waveform analysis monitor (PulseCO) with an indicator dilution technique (LiDCO) in patients in intensive care. Presented at the ICCM Sydney, October.

P2.3. Mappes A, Gruendel M, Kuppe M. (2001) Perioperative hemodynamic beat-to-beat monitoring of cardiac output: the new PulseCO System. Presented at the American Society of Anesthesiology, New Orleans Anesthesiology 95(3A): A-541

P2.4. Mappes, M. Gründel, J. Lindert, H. Kuppe (2001) Hemodynamic monitoring during cardiac surgery: Improved arterial pressure waveform analysis - the PulseCO System, Presented at: Institute of Anesthesiology- Deutsches Herzzentrum Berlin, Germany

P2.5. Roberts P, Allen S, Robinson S, Tanser S, Jonas M, Morgan M. (2002) Use of lithium dilution assessment of cardiac output to optimise right/left ventricular activation in resynchronisation therapy, Presented at: 80th Anniversary British Cardiac Society Annual Scientific Conference Harrogate. Published in Heart, May 2002: 87 Supplement II (Abstract 146)

P2.6. Velissaris T, Hett D, Gill R, Herbertson M, Jonas M, Ohri S. (2002) Hemodynamic advantages of right heart decompression during cardiac verticalization in beating-heart surgery, Abstract presented at: Annual Meeting of the Society of Cardiothoracic Surgeons of Great Britain & Ireland (SCTS)

P2.7. T. Velissaris, D. Hett, R. Gill, M. Herbertson, M. Jonas, S. Ohri (2002) Real-time monitoring of hemodynamic changes during beating-heart coronary surgery. Abstract presented at: Annual Meeting of the Society of Cardiothoracic Surgeons of Great Britain & Ireland (SCTS) & as letter: Eur J Cardiothorac Surg 22:852

P2.8. L. B. Heller, M. Fisher, N. Pfanzelter, D. Jayakar, V. Jeevanandam, S. Aronson. (2002) Continuous intraoperative cardiac output determination with arterial pulse wave analysis (PulseCO) is valid and precise. Presented at: The Society Of Cardiovascular Anesthesiologists New York. & Anesth. Analg 2002. 93:SCA 1-SCA 112

P2.9. Jonas M, Tanser S. (2002) Lithium dilution measurement of cardiac output and arterial pulse waveform analysis: an indicator dilution calibrated beat-by-beat system for continuous estimation of cardiac output. Current Opinion in Critical Care; 8 : 257 – 261

P2.10. Jonas M, Hett D, Morgan J. (2002) Real-time, continuous monitoring of cardiac output and oxygen delivery. International Journal of Intensive Care Spring Edition, Volume 9 Number 1

P2.11. Linton N, Linton R (2003) Haemodynamic response to a small intravenous bolus injection of epinephrine in cardiac surgical patients. European Journal of Anaesthesiology 20: 298-304

P2.12. Pearse, Ikram, Barry (2004) Equipment review: An appraisal of the LiDCOplus method of measuring cardiac output. Critical Care 2004, 8:190-195

P2.13. Tooley (2004) Blood Pressure is an Unreliable Marker of Tissue Perfusion. The Value of Continuous Non Invasive Monitoring of Cardiac Output. Poster presented at the Pediatric Academic Meeting, San Francisco, USA. [The use of the LiDCOplus Hemodynamic Monitor is unlicensed in patients of less than 40 kgs / 88Ilbs in weight]

P2.14. Kirwan C, Smith J, Lei K, Beale R (2005) A comparison of two calibrated continuous arterial pressure waveform based measurements of cardiac output over 24 hour. Crit Care Med. 33(12) Suppl; 208-S; A56

P2.15. Hallowell G, Corley K (2005) Use of lithium dilution and pulse contour analysis cardiac output determination in anestheized horses: a clinical evaluation. Vet Anaes & Analgesia 32, 201-211

P2.16. Berberian G, Quinn TA, Vigilance D, Park D, Cabreriza S, Curtis L, Spotnitz H. (2005) Validation Study of PulseCO System for Continuous Cardiac Output Measurement. ASAIO Journal 51: 37 – 40

P2.17. Kim JJ, Dreyer WJ, Chang AC, Breinholt III JP, Grifka RG (2006) Arterial pulse wave analysis: An accurate means of determining cardiac output in children. Paed Crit Care Med 7(6) 532-535 [The PulseCO algorithm is licensed for adult use only ]

P2.18. de Wilde RBP, Schreuder JJ, van den Berg PCM, Jansen JRC (2007) An evaluation of cardiac output by five arterial pulse contour techniques during cardiac surgery. Anaesthesia: 62, 760-768

P2.19. Meyhoff C, Hesselbjerg L, Koscielniak-Nielsen Z, Rasmussen L. (2007) Biphasic cardiac output changes during onset of spinal anaesthesia in elderly patients. European Journal of Anaesthesiology 24: 770 – 775

P2.20. Yamashita K, Nishiyama T, Yokoyama T, Abe H, Manabe M (2007) Effects of vasodilation on cardiac output measured by PulseCO. Journal of Clinical Monitoring and Computing 21: 335 – 339

P2.21. Lobo S, Oliveira N, Lobo F, Rezende E, Borges B, Cunrath G, Silva J, Ronchi L (2007) Oxygen delivery optimization using lithium indicator dilution and pulse power analysis during major surgery in high-risk patients. Poster Presentation ISICEM Brussels Critical Care, 11(2):P305doi:10.1186/cc5465.

P2.22. Dyer RA, Piercy JL, Reed AR, Lombard CJ, Schoeman LK, James MF (2008) Hemodynamic changes associated with spinal anesthesia for cesarean delivery in preeclampsia. Anesthesiology Vol. 108, No. 5, 802 – 811

P2.23. Cecconi M, Fawcett J, Grounds R, Rhodes A (2008). A prospective study to evaluate the accuracy of pulse power analysis to monitor cardiac output in critically ill patients. BMC Anesthesiology 8:3, 1 – 9

P2.24. Jonas M, Fennell J, Brudney CS. (2008). Haemodynamic optimsation of the surgical patient revisited. Anaesthesia International, Spring 2008 Vol 2 No1

P2.25. Archer T, Knape K, Liles D, Wheeler A, Carter B. (2008). The hemodynamics of oxytocin and other vasoactive agents during neuraxial anesthesia for cesarean delivery: findings in six cases. Int. J. Obstetric Anesthesia Vol. 17:3, 247-254.

P2.26. Murugan R, Venkataraman R, Wahed A, Elder M, Carter M, Madden N, Kellum J (2009) preload responsiveness is associated with increased interleukin-6 and lower organ yield from brain-dead donors. Crit Care Med Vol. 37 No. 8, 2387 – 2393

P2.27. Kim H, Hadian M, Severyn D, Pinsky M (2009). Cross-comparison of the trending accuracy of continuous cardiac output measurement devices in postoperation patients. Poster presentation ISICEM, Brussels. Critical Care, 13(Suppl 1):P209doi:10.1186/cc7373

P2.28. Meyhoff C, Haarmark C, Kanters J, Rasmussen L (2009) Is it possible to predict hypotension during onset of spinal anesthesia in elderly patients? Journal of Clinical Anesthesia 21, 23-29

P2.29. Haslam G, Kelly F, English W, D’Agapeyeff A, Padkin A, Cook T, Nolan J (2009) Comparison of three noninvasive cardiac output monitoring in patients undergoing therapeutic hypothermia after cardiac arrest. Poster presentation ISICEM, Brussels. Critical Care,
13(Suppl 1):P210doi:10.1186/cc7374

P2.30. Eley K, Young D, Watt-Smith S (2009) Assessment of the effects of pressors on graft blood flow after free tissue transfer surgery: interim findings. Brit Journal of Oral and Maxillofacial Surgery Vol 47 Issue 7 e41 – e42

P2.31. Eley K, Watt-Smith S (2009) Intra-operative use of LiDCO – is there an effect on the volume of intravenous fluids used by anaesthetists during free flap surgery for head and neck cancer? Brit Journal of Oral and Maxillofacial Surgery Vol 47 Issue 7 e15

P2.32. Eley K, Watt-Smith S (2009) Re: Postoperative fluid balance in patients having operations on the head and neck. Letter to the Editor. Brit Journal of Oral and Maxillofacial Surgery Vol 47 Issue 7 p249

P2.33. Maisenbacher H, Estrada A, Prosek R, Shih A, VanGilder J (2009) Evaluation of the effects of transvenous pacing site on left ventricular function and synchrony in healthy anesthetized dogs. American Journal of Veterinary Research 70: 455 – 463

P2.34. Shih A, Giguere S, Sanchez L, Valverde A, Jankunas H, Robertson S (2009) Determination of cardiac output in anesthetized neonatal foals by use of two pulse wave analysis methods. American Journals of Veterinary Research 70: 334 – 339

P2.35. Langesaeter E, Rosseland L, Stubhaug A (2009) Haemodynamic Effects of Repeated Doses of Oxytocin During Caesarean Delivery in Healthy Parturients, Br J Anaesthesia 103(2):260-262

P2.36. Dizon J, Quinn TA, Cabreriza S, Wang D, Spotnitz H, Hickey K, Garan H (2010) Real-time Stroke Volume Measurements for the Optimization of Biventricular Pacing Parameters. Submitted for publication

P2.37. Jain A, Dutta A (2010) Stroke Volume Variation as a Guide to Fluid Administration in Morbidly Obese Patients Undergoing Laparoscopic Bariatric Surgery. Obes Surg DOI 10.1007/s11695-009-0070

P2.38. Carter J, Campbell N, Popsner L, Swanson C (2010) The hemodynamic effects of medetomidine continuous rate infusions in the dog. Veterinary Anaesthesia and Analgesia 37(3) 197 – 206

P2.39. Bisgaard J, Ronholm E, Gilsaa T, Toft P (2010) Optimizing stroke volume and oxygen delivery in elective abdominal aortic surgery. Poster presentation ISICEM, Brussels. Critical Care 14(Suppl 1):P120doi:10.1186/cc8352

P2.40. De Wilde R, Geerts B, Van den Berg P, Jansen J (2010) Continuous cardiac output measurement: effect of time. Poster presentation ISICEM, Brussels. Critical Care 14(Suppl 1):P106doi:10.1186/cc8338

P2.41. Martin-Bouyer V, Schauvliege S, Duchateau L, Bosman T, Gasthuys F, Polis I (2010) Cardiovascular effects following epidural injection of romifidine in isoflurane-anaesthetized dogs. Veterinary Anaesthesia and Analgesia 37: 87 – 96

P2.42. Salvato, K, Gillis B. (2010) Nephrotic syndrome and superimposed preeclampsia in a preterm parturient: Successful utilization of the LiDCO monitor. Poster presentation Society for Obstetric Anaesthesia & Perinatology, San Antonio, May.

P2.43. Archer T, Heitmeyer J. (2010) Perioperative hemodynamics obtained by pulse contour analysis facilitated the management of a patient with chronic hypertension, renal insufficiency, and superimposed preeclampsia during cesarean delivery. J. Clinical Anesthesia 22(40, 274-279

P2.44 Velissaris T, Jonas M, Ohri S. (2010) Hemodynamic advantages of right heart decompression during off-pump cardiac surgery. Asian Cardiovasc Thorac Ann 18:17-21

P2.45. Dyer R (2010) Maternal haemodynamic monitoring in obstetric anaesthesia. Anaesthetic Foundation Refresher Course, Capetown University

P2.46. Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds C, Pearse R (2010) Haemodynamic optimsation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial. Critical Care 14: R151 doi:10.1186/cc9220

P2.47. Dyer R, Reed A, van Dyk D, Arcache M, Hodges O, Lombard C, Greenwood J, James M (2009) Hemodynamic Effects of Ephedrine, Phenylephrine, and the Coadministration of Phenylephrine with Oxytocin during Spinal Anesthesia for Elective Cesarean Delivery. Anesthesiology 111:753-65

P2.48. Cecconi M, Monti G, Dawson D, Vamadan S, Hamilton M, Della Rocca G, Grounds RM, Rhodes A (2009) Dynamic indices by PulseCO in post surgical intensive care patients. Proceedings of the 2009 Annual Meeting of the ESICM

P2.49. Hannegard-Hamrin T, Odeberg-Wenerman S (2010) Lithium indicator technique for cardiac output in children: reproducibility of the calibration factor. Proceedings of the 2010 Annual Meeting of the ESICM

P2.50. Marcilla M, Schauvliege S, Duchateau L, Gasthuys F (2010) Cardioplumonary effects of two constant rate infusions of dexmedetomidine in isoflurane anaesthetized ponies. Veterinary Anaesthesia and Analgesia 37 (4) 311 – 321

P2.51. Andersson L, Bartha E, Fernlund E, Arfwedson C, Kalman S (2010) The efficacy of an algorithm for goal-directed haemodynamic treatment (GDHT) to elderly patients with proximal femoral fracture: 18AP1-6. Eur Journal of Anaesthesiology 27 (47) 242

P2.52. Beattie C, Moores C, Thomson A, Nimmo A (2010) The effect of anaesthesia and aortic clamping on cardiac output measurement using arterial pulse power analysis during aortic aneurysm repair. Anaesthesia 65 (12) 1194 – 1199

P2.53. Heijmans J, Ganushak Y, Theunissen M, Maessen J, Roekaerts P (2010) Predictors of cardiac responsiveness to fluid therapy after cardiac surgery. Acta Anaesthesiol Belg 61 (3) 151 – 8

P2.54. Kaartinen J, Pang D, Moreau M, Vainio O, Beaudry F, del Castillo J, Lamont L, Cuvelliez S, Troncy E (2010) Hemodynamic Effects of an Intravenous Infusion of Medetomidine at Six Different Dose Regimens in Isofluorane-Anesthetized Dogs. Veterinary Therapeutics 11 (1) E1 – E16

P2.55. Skhirtladze K, Mora B, Moritz A, Birkenberg B, Ankersmit H, Dworschak M (2010) Impaired recovery of cardiac output and mean arterial pressure after successful defibrillation in patients with low left ventricular ejection fraction. Resuscitation 81 (9) 1123 – 1127

P2.56. Langesaeter E, Dragsund M, Rosseland L (2010) Regional anaesthesia for a Caesarean section in women with cardiac disease: a prospective study. Acta Anaesthesiol Scand 54 46 – 54

P2.57. Cecconi M, Dawson D, Casaretti R, Grounds R, Rhodes A (2010) A prospective study of the accuracy and precision of continuous cardiac output monitoring devices as compared to intermittent thermodilution. Minerva Anestesiologica 76 1 - 8

P2.58. Powner D, Hergenroeder G (2011) Measurement of cardiac output during adult donor care. Progress in Transplantation 21 (2) 144 – 150

P2.59. Cecconi M, Caliandro F, Barbon E, Elliott V, Dewhurst, Rhodes A (2011). Delta central venous pressure and dynamic indices of preload in post surgical ICU patients. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P49 doi:10.1186/cc9469

P2.60. Barbon E, Caliandro F, Kamdar J, Puntis M, Meeran H, Rhodes A, Dewhurst A, Cecconi M (2011) Dynamic indices of preload in postcardiac surgery patients by pulse power analysis. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P54 doi:10.1186/cc9474

P2.61. Costa M, Cecconet T, Chiarandini P, Buttera S, Pompei L, della Rocca G (2011) Comparison of stroke volume changes of LiDCOplus and Flotrac during postoperative hemodynamic optimization. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P59 doi:10.1186/cc9479

P2.62. Brass P. Mills E, Latza J, Peters J, Berendes E (2011) LiDCOrapid and PiCCOplus preload response parameter validation study. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P61 doi:10.1186/cc9481

P2.63. Brass P. Mills E, Latza J, Peters J, Berendes E (2011) Comparison of cardiac index: LiDCOrapid and PiCCOplus in the ICU. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P62 doi:10.1186/cc9482

P2.64. De Santis P, Marano C, Cavallaro, Dell’Anna A, Bonarrigo C, Falcone C, Sandroni C (2011). Prediction of fluid responsiveness with the LiDCO system. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P64 doi:10.1186/cc9484

P2.65. Willars C, Dada A, Green D (2011). Functional haemodynamic monitoring: the relative merits of SVV, SPV and PPV as measured by the LiDCOrapid in predicting fluid responsiveness in high-risk patients. Proceedings of 31st International Symposium on Intensive Care and Emergency Medicine 15 (Suppl 1):P66 doi:10.1186/cc9486

P2.66. Riha H, Kotulak T, Syrovatka P, Netuka I (2011) eComment: Hemodynamic monitoring with LiDCOplus system in the patients supported by isolated right ventricular assist device. Communication Interact CardioVasc Thorac Surg 13 p57.

P2.67. Langesaeter E, Rosseland L, Stubhaug A (2011). Haemodynamic effects of oxytocin in women with severe preeclampsia. Intl Jnl of Obstetric Anesthesia 20 (1) 26 – 29

P2.68. Langesaeter E, Dyer R (2011). Maternal haemodynamic changes during spinal anaesthesia for caesarean section. Current Opinion in Anaesthesiology 24 (3) 242 - 248

P2.69. Passos R, Batista P (2011) Fluid removal in critically ill patients during hemodialysis: is there a role for functional hemodynamic monitoring? Proceedings of the 6th International Symposium on Intensive Care and Emergency Medicine for Latin America 15 (suppl 2): P30 doi:10.1186/cc10178

P2.70 Eide P (2011) Cardiac output in idiopathic normal pressure hydrocephalus: association with arterial blood pressure and intracranial pressure wave amplitudes and outcome of shunt surgery. Fluids and Barriers of the CNS 8 (11) 1-10

P2.71 Geerts B, Aarts L, Groeneveld A, Jansen J. Predicticting cardiac output responses to passive leg raising by a PEEP-induced increase in central venous pressure, in cardiac surgery patients. British Journal of Anaesthesia 107 (2): 150-6

P2.72 Singh S, Kuschner W, Lighthall G. (2011) Perioperative intravascular fluid assessment and monitoring: a narrative review of established and emerging technologies. Anesthesia Research and Practice Article ID 231493, doi:10.1155/2011/231493

P2.73 Hamilton M, Cecconi M, Rhodes A. (2011) A systematic review and meta-analysis on the use of pre emptive hemodynamic intervention to improve postoperative outcomes in moderate and high risk surgical patients. Anesthesia and Analgesia June vol. 112:(6) 1392 -1402

P2.74 Lee A, Cohn J, Ranasinghe S. (2011) Cardiac output assessed by invasive and minimally invasive techniques. Anesthesia Research and Practice Article ID 475151, doi:10.1155/2011/475151

P2.75 Geerts B, Aarts L, Jansen J. (2011) Methods in pharmacology: measurement of cardiac output. British Journal of Clinical Pharmacology vol 71 (3): 316 – 330

P2.76 Potocnik I, Jankovic V, Kremzar B, Stupnik T. (2011) Haemodynamic change after induction of anaesthesia with sevoflurane vs. propofol. Signa Vitae vol 6(2): 52-57

P2.77 Mora B, Ince I, Birkenbrerg B, Skhirtladze K, Pernicka E, Ankersmit H, Dworschak M. (2011) Validation of cardiac output measurement with the LiDCO pulse contour system in patients with impaired left ventricular function after cardiac surgery. Anaesthesia vol 66(8): 675-681

P2.78 De Santis P, Marano C, Cavallaro F, Dell’Anna A, Santis P, Bonarrigo C, Falcone C, Sandroni C. (2011) Prediction of fluid responsiveness with the LiDCO system. Crit Care 15(Suppl 1):p64

P2.79 Alhashemi A, Cecconi M, Hofer C. (2011) Cardiac output monitoring: an integrative perspective. Critical Care 15:214

P2.80 Chalmers A, Turner M, Anand R, Puxeddu R, Brennan P. (2011) Cardiac output monitoring to guide fluid replacement in head and neck microvascular free flap surgery – what is current practice in the UK? British Journal of Oral and Maxillofacial Surgery doi:10.1016/j.bjoms.2011.08.010

P2.81 Bundgaard-Nielsen M, Holte K, Secher N, Kehlet H. (2007) Monitoring of peri-operative fluid administration by individualized goal-directed therapy. Acta Anaesthesiol Scand Mar; 51(3):331-40

P2.82 Lees N, Hamilton M, Rhodes A. (2009) Clinical review: Goal-directed therapy in high risk surgical patients. Critical Care 13:231 doi:10.1186/cc8039

P2.83 Holmes T, Williams D. (2010) Cardiac output measurement. Anaesthesia and Intensive Care Medicine 11 (2): 58-61

P2.84 Shah A, Oelofse T. (2010) Advanced cardiovascular monitoring. Surgery 28 (4): 165-170. Surgery 28 (4): 165 – 170

P2.85 Richard K, Novak M, Quill T, Cannesson M. (2010) Functional Hemodynamics during High Risk Abdominal Surgery: Are All Monitors Created Equal? Proceedings of the 2010 Annual Meeting of the American Society Anesthesiologists

P2.86 Avery S, Mills E, Jonas M, Margason M. (2010) PulseCO Derived Stroke Volue Variation for Prediction of Fluid Responsiveness in the Morbidly Obese. Proceedings of the 2010 Annual Meeting of the American Society Anesthesiologists

P2.87 Miller M, Kumar A, Callison C (2011) Refractory caffeine and ergot-induced cervico-cerebral vasospasm and stroke treated with combined medical and endovascular approach. Neuroradiology Apr; 54(1): 77-9

P2.88 Haskins S (2011) Output performance: cardiac output by pulse contour analysis. Journal of Veterinary Emergency and Critical Care 21: 305 – 308

P2.89 Osawa E, Rhodes A, Fukushima J, Almeida J, Jatene F, NakamuraR, Sundin M, Auler Jr J, Kalil Filho R, Galas F, Hajjar L (2012) Goal-directed Hemodynamic Resuscitation in High Risk Patients Undergoing Cardiac Surgery – a randomized controlled trial – preliminary data (GRICCS STUDY) Critical Care 16 (Suppl 1) :P197 doi:10.1186/cc10804

P2.90 Jorgensen H, Bisgaard J, Gilsaa T (2012) Cardiac output monitoring using the LiDCOplus monitor in abdominal aortic surgery – changes in calibration factor in aortic aneurysm disease versus aortic occlusive disease. Critical Care March 16: P223

P2.91 Beauchamp N, Mowat I, Dickinson M. (2012) Outcomes in emergency laparotomies: local results and response to a national audit. Presented at the January 2012 Winter Scientific Meeting of the AAGBI, London